Colin Fuller

Colin's CV

The higher-order structure of chromatin has been seen to affect gene regulation, development, chromosome segregation, and any number of other cellular processes. Currently, there is a gap in our abilities to systematically study chromatin structure:
in vitro methods provide high-resolution data on isolated structures that may not be relevant within living cells, while in vivo methods can only reliably map structures
to the resolution of several hundred basepairs-- a limit well above the scale of the fundamental unit of chromatin, the nucleosome.

I am working on developing a biochemical technique for mapping chromatin structure
to nucleosome-level resolution that will operate both in vitro and in vivo, and using this technique to ask whether in vitro assembled chromatin structures are relevant in living cells, what the determinants of in vivo chromatin structure are, and what effects changes in chromatin structure in isolation can have on cellular processes.

Favorite band?
Aimee Mann

Type of toothpaste?
AIM, but I use Crest

Best place to go on a sunny day?
Wet chemistry room

Burrito or mojado style?
Mojado style

Favorite piece of lab equipment?
Separation funnel