| Cytokinesis – Mitosis isn’t finished until the segregated chromosomes are encapsulated in new cellular compartments. During the process of cytokinesis, the cell membrane is constricted between the newly segregated chromosomes and the membrane of the cell is fused to create two new cells and ensure that the daughter cells obtain an equal chromosomal complement. Cytokinesis is exquisitely choreographed so that the position of the mitotic apparatus delineates the position of the furrow. We are interested in understanding how the interplay between the microtubule cytoskeleton, the chromosomes, the actin cytoskeleton, and the cell membrane is coordinated to ensure proper contractile ring placement and cell cleavage.
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